Name: Yoshiharu Y. Yamamoto

My Area of Interest: plant promoters, environmental responses, intergenomic interaction

My Favourite Quote: Desire to be a teacher is everyone’s illness.

I am a: research associate

Short Profile:
I used to study environmental adaptation of higher plants. When I tried microarray analysis in 2001, the established methods for de novo detection of cis-regulatory elements were not practical. Such a situation moved me to general promoter analysis. With my developed method, many promoter constituting sequences can be extracted, and it does not require much experimental information.
- ppdb, a plant promoter database
   Yamamoto YY, Obokata J. (2008) Nucleic Acids Res 36, D977-D981.
- Differentiation of core promoter architecture between plants and mammals revealed by       LDSS  analysis
 Yamamoto YY*, Ichida H, Abe T, Suzuki Y, Sugano S, Obokata J. Nucleic Acids Res (2007)35,   6219-6226.
-Identification of plant promoter constituents by analysis of local dstribution of short  sequences
  Yamamoto YY*, Ichida H, Matsui M, Obokata J, Sakurai T, Satou M, Seki M, Shinozaki K, Abe T  (2007) BMC Genomics 8:67.
-Gene trapping of the Arabidopsis genome with a firefly luciferase reporter
  Yamamoto YY, Tsuhara Y, Gohda K, Suzuki K, Matsui M. (2003). Plant J 35, 273-283.

What are your future goals? Where do you see your research going?:
I would like to know evolutional paths for promoter acquisition and maturation after gene transfer from organellar genomes to the nuclear genome.

Technologies seem to changing faster than ever, how do you adapt to that? What are the current technologies you are using?:
Open mind for wide knowledge and concentration on works. I am using next-generation sequencers.

In the broader picture, where do you see the application for your cutting-edge research?:
Genome interpretation and genome annotation.

Fast forward to 2020. What’s your vision of Genomics in 2020?:
Major problems regarding macro and micro evolution might have good answers. Synthetic biology might be a major research area, like current chemistry.