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Dr. Rama Shankar Verma

9 April 2010 No Comment

Associate Professor, Department of Biotechnology, IIT, Chennai

Immunotoxins are chimeric proteins with a cytotoxic protein linked to a cell-targeting moiety such as a cytokine or monoclonal antibody. Immunotoxins offer means for selective targeting and elimination of cancer cells over-expressing specific cell surface receptors. After binding to target cells, these proteins are internalized by receptor -mediated endocytosis and cell death is induced by the toxin moiety.

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