Name: Giovanni Roviello

My Area of Interest: DNA and RNA recognition by nucleopeptides

My Favourite Quote: No man ever steps in the same river twice, for it’s not the same river and he’s not the same man. (Heraclitus)

I am a:Researcher

Short Profile:

What are your future goals? Where do you see your research going?:
I plan to develop new nucleopeptides able to interact, by means of specific nucleobase-pairing, with complementary DNA molecules of therapeutical importance for antigene applications. Furthermore, new antisense molecules will be realized to block gene expression in specific biomedical strategies.
The nucleopeptides of my interest are made of building blocks that are molecules found extraterrestrially in meteorites and supposed to have been part of a prebiotic genetic material, that would have preceded the actual nucleic acids.
Thus, my research will be also important in the field of Prebiotic Functional Genomics, a young branch of the science that will elucidate the mechanims that produced the actual nucleic acids/proteins world.

Technologies seem to changing faster than ever, how do you adapt to that? What are the current technologies you are using?:
Technologies I’m using comprise Circular Dichroism, Mass Spectroscopy, Gel electrophoresis, solid phase synthesis

In the broader picture, where do you see the application for your cutting-edge research?:
The applications I see for my innovative research include biomedical strategies making use of bioinspired beta, gamma, and epsilon-peptides functionalized by nucleobase as well as of novel nucleopeptides with prebiotic importance that could throw light on the bioevolution, allowing, not less importantly, for the de sign of novel challenging strategies in biotechnology.

Fast forward to 2020. What’s your vision of Genomics in 2020?:
Genomics will promote the understanding of the function and evolution of genomes in all kingdoms of life. Genome sciences and technologies will approach and solve several challenging problems in biology and medicine.